Henry Meds Reviews

We review Henry Meds to see if you could benefit from its weight loss, insomnia, or testosterone treatments.

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Last updated: Jun 26th, 2024
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Wegovy vs Mounjaro Henry Lineup

Photo by Innerbody Research

Ozempic, Wegovy, Mounjaro, and similar medications have become must-haves in the minds of many Americans — so much so that their popularity has contributed to a significant shortage. Their popularity has also created an online ecosystem of telehealth providers that can get you a prescription for these medications and connect you with compounding pharmacies to access generic versions of them.

In most cases, the companies offering the prescriptions and the pharmacies filling them are safe and above board. But there are some companies using inferior ingredients and angling to take your money and run, all while putting your health at risk.

Henry Meds belongs to the safe and above-board group, and while that’s comforting, it might not be enough to tell you whether it’s the best place for you to go in search of weight loss medications or Henry’s other offerings like testosterone therapy or insomnia treatment.

That’s why our team did a deep dive into the marketplace and tried Henry for ourselves so that we can relay all the pros, cons, and details of this telehealth service.

Our Findings

Editor's Rating4.00

Pros

  • Oral versions of semaglutide (Ozempic, Rybelsus, and Wegovy) and tirzepatide (Mounjaro and Zepbound) available
  • Less expensive than most competitors
  • Three insomnia treatments available
  • Testosterone replacement therapy (TRT) available as an injection or cream
  • Consultation process is straightforward and not at all invasive
  • Shipping is exceptionally fast

Cons

  • Starting doses are likely on the low side for many oral GLP-1 medications
  • Dose increases cost more than advertised rates
  • Some GLP-1 medications require injection with a traditional syringe
  • Poor quality oral syringes provided with some liquid drops
  • Some insomnia treatments may have dangerous side effects
  • Money-back guarantee might not be long enough to notice results

Henry Meds offers treatment plans for weight loss, insomnia, and low testosterone, most of which include viable medications for low prices. Its prices for GLP-1 treatments (generics for Ozempic, Mounjaro, and others) are among the lowest in its class. You can also access some of these drugs as oral medications, negating the need to use a needle. And since you don’t have to pay an additional membership fee to access its goods and services, Henry could be a smart choice for many people.

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Why you should trust us

At Innerbody Research, we extensively test each health service we review whenever possible, including Henry Meds. Our team has dedicated extensive time to researching the issues Henry seeks to treat, especially testosterone and weight loss. All told, we’ve read more than 100 scholarly articles on testosterone deficiency and treatment, as well as nearly 100 more on various weight loss approaches, including GLP-1 receptor agonists like the ones Henry offers.

We’ve also accessed and tried Henry's products for ourselves, testing the company's customer support capabilities in the process. This gives us unique insights into the customer experience, which we can then share with you. Additionally, like all health-related content on this website, this guide was thoroughly vetted by one or more members of our Medical Review Board for accuracy, and our editorial team will continue to monitor it for updates.

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

How we evaluated Henry Meds

We concentrated our attention on four key criteria while evaluating Henry Meds, which we developed while trying the service ourselves. Among them are Henry’s available medications, which put the company in a specific place compared to direct competitors. We also considered cost, safety, and our evaluation of the customer experience.

Let’s take a closer look at how Henry Meds performed in each category.

Available medications

Rating: 8.6 / 10

Henry offers treatment for three issues: overweight and obesity, insomnia, and low testosterone. Henry's weight loss program comprises a greater diversity of medications and delivery mechanisms than its other two treatment lanes and appears to be a significant part of the company's business.

Most of the weight loss meds that Henry offers are glucagon-like peptide-1 receptor antagonists (GLP-1 RAs). These are some of the most popular weight loss drugs on the market right now, often sold as recognizable brand names like Ozempic, Wegovy, and Mounjaro. While you can get these brand-name versions from certain online retailers (with and without insurance), Henry offers compounded versions of their generic active ingredients instead. This makes them more accessible despite an ongoing shortage among brand-name GLP-1 RAs.

Specifically, Henry’s GLP-1 RAs include:

Generic for...Delivery mechanisms
SemaglutideOzempic, Wegovy, RybelsusInjection, oral tablets, oral drops
LiraglutideSaxenda, VictozaInjection
TirzepitideMounjaro, ZepboundInjection, oral drops

Henry’s insomnia treatments include three oral medications also sold as generics, all of which are available in pill form. They include:

  • Hydroxyzine pamoate: generic for Vistaril
  • Trazodone: generic for Oleptro
  • Mirtazapine: generic for Remeron

Compared to its weight loss and insomnia treatments, Henry’s approach to testosterone therapy is a little more limited. The company offers testosterone cypionate injections, which boast a high degree of efficacy for men with low testosterone. You can also get a topical testosterone cream from Henry, but other treatments on the market — like prescription clomiphene or enclomiphene from Roman or Maximus Tribe — may prove superior, especially in terms of safety and convenience. Both are oral medications that are more convenient than testosterone injections, creams, or gels and come with less intense side effect risks.

Ultimately, Henry’s lineup is best suited for people without insurance looking to lose weight with medical intervention or people with sleep issues who prefer the convenience of telemedicine. Men specifically seeking testosterone cypionate will be pleased with Henry's pricing, which we’ll discuss below, but we’d guide men new to testosterone replacement therapy (TRT) to less aggressive alternatives to start.

Cost

Rating: 8.4 / 10

Using generic active ingredients allows Henry to keep costs down and provide reasonably priced service for people without insurance. Compared to direct competitors, Henry has better prices at just about every level. There are some caveats, however.

When we look at the competitive landscape for GLP-1 RAs as a sample, we find there are three types of providers online: those that offer brand-name drugs only, those that offer generic drugs only, and those that offer both. We’ve excluded the companies that only offer brand-name drugs from this analysis, as the prices simply aren’t comparable, and there aren’t many good reasons to use these companies for branded GLP-1 RAs instead of just going to the doctor if you have insurance. That’s because many of these companies, no matter what kind of weight loss drugs they offer, charge monthly membership fees that don’t cover the cost of medication.

For example, if you wanted Ozempic, and you decided to get it from Mochi, you’d pay a $79 monthly fee on top of the cost of medication. If your copay is less than $79, it obviously makes more sense to go to a doctor in person if you’re able. That is especially true when you consider that copays are one-off costs that you don’t have to pay monthly.

However, those monthly fees pay for something that copays cannot, and that’s recurrent access to a medical professional throughout treatment. Instead of having to make a follow-up appointment and return to your doctor’s office, you can simply message your consulting physician online. There’s an undeniable convenience there, but Henry may offer the best of both worlds.

Here’s what the GLP-1 RA landscape looks like:

Monthly membership costsCompounded medications (monthly)Brand name medications (prices vary by insurance)
Henry MedsNoneTirzepatide: $299 (oral), $399 (injection); semaglutide: $199 (oral), $247 (injection); liraglutide: $247N/A
EdenNoneTirzepatide: $396; semaglutide: $246 (oral), $296 (injection)Wegovy, Mounjaro, Ozempic, Zepbound
HimsNoneSemaglutide: $399Wegovy, Ozempic
StrutNoneSemaglutide: $349 (oral), $289-$469 (injection)N/A
Ivy RXNoneTirzepatide: $495; semaglutide: $297 (oral), $295 (injection)Mounjaro, Ozempic
Ro$145 ($99 first month)Semaglutide: $450Wegovy, Ozempic, Zepbound, Saxenda
Mochi$79Tirzepatide: $325, semaglutide: $175Wegovy, Mounjaro, Ozempic, Zepbound, Saxenda, Xenical, Contrave, Victoza, and more
PlushMembership: $17, consultations: copay or $129Tirzepatide: $299-$749, semaglutide: $299-$599Wegovy, Mounjaro, Ozempic, Zepbound, Saxenda, Xenical, Contrave, Victoza
Zealthy$135 ($49 first month)Tirzepatide: $216, semaglutide: $151Wegovy, Mounjaro, Ozempic, Zepbound

As you can see, Henry is among a group of providers offering services without additional monthly fees. What’s more, it offers the same kind of provider access throughout treatment that you’ll get from the companies that have those steep fees.

On top of its free monthly structure, most of Henry’s medication prices are unbeatable, though the difference one way or the other is rarely more than a few dollars. This pattern plays out similarly across Henry’s catalog.

Most of Henry’s competitors offer similar drugs, though Henry is rare in its offering oral tablets and sublingual drops for multiple GLP-1 medications. Compared to giving yourself weekly injections at home, these medication formats can improve safety by mitigating the risk of infection or tissue damage from the needle. Eden, Ivy RX, and Strut offer oral versions of semaglutide, but only Eden comes close to Henry for cost.

One knock against Henry’s setup is that its prices may go up if you need a higher dose than what’s typically prescribed. For the injectable GLP-1 RAs, this shouldn’t be much of an issue, as the company’s dosing aligns nicely with the research. But the oral GLP-1 medications may be underdosed for some, which would lead to a monthly increase of $100 on those plans.

Henry’s pricing for its other medications is about on par with the competition, though competitor RedBoxRx offers a couple of extra insomnia treatments at a potentially lower cost, depending on what your consulting physician prescribes.

Safety

Rating: 7.5 / 10

Like any of the companies providing compounded generic medications, the safety of those treatments will align with the quality of the compounding pharmacy the company uses. We’ve identified two compounding pharmacies in Henry’s portfolio, both of which are in step with FDA regulations and should produce drugs therapeutically identical to brand-name equivalents.

So, our first consideration when evaluating the safety of Henry’s treatments involves assessing the medications it’s chosen to include in its catalog and scrutinizing research into their potential adverse effects and contraindications. Some of those risks are noteworthy despite GLP-1 RAs’ good track record in studies, including potential increases in thyroid cancer risk and the possibility of pancreatitis.

The decision to offer only testosterone cypionate or testosterone cream as low testosterone treatments when there are other, potentially safer, places for men to start dinged the company’s score here a bit. So, too, did its inclusion of trazodone for insomnia, which has a controversial safety profile.

In our testing experience, we found it incredibly easy to get a GLP-1 RA prescription. That may have boosted the company’s rating below in our customer experience section, but we would have liked to see Henry’s doctors ask for the same kinds of mandatory test results you’ll often be required to submit at a doctor’s office, including blood sugar and thyroid numbers. The company requires a testosterone test for a TRT prescription, so adding a similar requirement here could increase safety. To be fair, we’ve only seen this requirement enforced by Roman for GLP-1 medications, and it charges a $75 fee for testing on top of the membership and medication costs.

Customer experience

Rating: 7.7 / 10

Our initial interactions with Henry were positive. Any potential patient arriving at the website will find it informative and easy to navigate, with clearly listed prices throughout. That’s certainly more than we can say for some providers, like Strut, whose pricing is attractive at the outset but gets more convoluted as you titrate up to a maintenance dose.

Making an appointment with a Henry medical professional was easy enough, though there wasn’t availability for a week from our sign-up date. One of the advantages of telemedicine is supposed to be its speed compared to the long waits to see doctors in the real world. One week is still faster than many real-world appointments, but it was slower than we expected.

One of our testers ran into a glitch during signup that made the system skip over the part where he needed to upload a copy of his driver’s license. Normally, this wouldn’t be a big deal, but this is where we get to the weakest current aspect of Henry’s service: the patient dashboard.

We’ve used a lot of telemedicine platforms throughout our years of testing, and this is one of the most bare-bones setups we’ve seen. It’s confusing to navigate and lacks some basic features that would be helpful. In the case of this ID glitch, there was no way to return to any aspect of the intake, nor was there any prompt regarding the missing images. This resulted in the appointment being canceled and our tester having to reschedule for another week away.

Signup processes and patient portals from companies like Hims or Roman are noticeably more polished, not just in their appearance but in their functionality.

The poor design of this interface also complicates cancellation — nowhere on the patient dashboard is it possible to initiate a cancellation. You actually have to go back to the main consumer-facing part of the website to find a link at the bottom of the page that initiates the process.

Henry Meds Cancelation Button

What is Henry Meds?

Telemedicine is largely made up of two kinds of companies: those with a niche focus and those that want to do it all. Henry is decidedly the former, focusing on weight loss, testosterone support, and sleep therapy. That focus doesn’t always translate to an improved customer experience or better prices, but it seems to have certain benefits for Henry customers.

Compared to prices from similar niche companies and some of the telehealth behemoths out there, Henry offers some remarkable deals, especially on generic GLP-1 RAs and testosterone replacement. And its focus on fewer treatments has allowed it to expand its available medication formats faster than others. Henry was one of the first to offer sublingual liquid versions of semaglutide and tirzepatide for weight loss.

Henry Meds online reputation

If all you went by to assess Henry Meds’ parent company, Adonis Health, was its Better Business Bureau page, you might run in the opposite direction. It’s listed with an F rating from the BBB, and it has no customer reviews and 12 complaints in the last year. Upon closer inspection, those customer complaints are largely related to the slow pace of weight loss or disputes over guarantee claims.

The picture is much different on Trustpilot, where Henry has more than 4,500 reviews that result in an average rating of 4.7 stars. Based on our personal testing experience, this is slightly higher than we regard Henry’s products and services. It’s actually higher than we’ve seen most companies achieve. Hims, a rival telemedicine provider that also offers weight loss drugs, has just a 3.2-star rating. Ro, a similar company offering weight loss support and testosterone therapy, has a 3.9-star rating. By comparison, Henry’s 4.7 stars is an impressive feat.

What medications does Henry Meds offer?

Henry Meds has a focused lineup of medications offering treatments for three issues:

  • Overweight and obesity
  • Low testosterone
  • Insomnia

Among those three areas, it’s Henry’s weight loss drugs that offer some of the most variety and best deals for potential patients. Most of these drugs belong to a class that has recently exploded in popularity thanks to brand names like Ozempic and Wegovy. The company's approach to its other two lanes of treatment is a little more traditional.

Let’s take a look at each of these medication categories to learn more about what you can get from Henry Meds.

GLP-1 receptor agonists

Henry Semaglutide and Ondansetron

Photo by Innerbody Research

GLP-1 RAs are better known by their popular brand names, like Ozempic or Mounjaro. Henry offers three of these drugs in their generic forms. Normally, you wouldn’t be able to get generic versions of drugs like these this early in their lifecycle, as generics aren’t typically available until after a drug company’s patent expires. However, a shortage of these drugs has allowed compounding pharmacies to produce them in their generic form, making them more accessible to a wider range of people for less money.

You can get three GLP-1 RAs from Henry:

Generic for:Available as:
SemaglutideOzempic, WegovyInjection, oral tablet, sublingual drops
TirzepatideMounjaro, ZepboundInjection, sublingual drops
LiraglutideSaxenda, VictozaInjection

Here are more details about these three medications.

Semaglutide

Semaglutide is one of the most popular GLP-1 drugs, and its predominant brand name, Ozempic, has become synonymous with the drug class. The drug has endured numerous clinical trials, one of the largest of which saw a 15.8% reduction in body weight after 68 weeks. For a 250lb person, that would equate to a loss of 39.5 pounds in a little over a year.

Tirzepatide

In addition to being a GLP-1 receptor agonist, tirzepatide also agonizes receptors for glucose-dependent insulinotropic peptide (GIP). GIP is responsible for your pancreas’ release of glucagon, which acts as a check against insulin and may improve blood sugar balance in conjunction with GLP-1 RA activity. Research indicates that this combination works better than GLP-1 RAs alone in pursuit of weight loss. One study pitting semaglutide against tirzepatide saw the tirzepatide group lose 5.4% more body weight than the semaglutide group after 72 weeks.

Liraglutide

Of the three GLP-1 RAs in Henry’s catalog, liraglutide may be the weakest. It produces results, but in a head-to-head comparison with semaglutide, it only caused a 6.4% reduction in body weight. You might think that would at least coincide with a superior safety profile, but that same study saw a greater rate of trial discontinuation due to adverse effects in the liraglutide group than in the semaglutide group. Liraglutide may be an option for certain patients with specific contraindications to the other drugs available, but that will depend on the results of your doctor’s appointment.

How do GLP-1 medications work?

The GLP in GLP-1 stands for glucagon-like peptide. GLP-1 is a peptide your body releases when you eat, and it causes your pancreas to create insulin to gobble up the glucose that food sends into your bloodstream. This is how GLP-1 receptor agonists work their magic. By mimicking the action of GLP-1, they instigate an increased insulin response to the food you eat, allowing those with Type-2 diabetes better control over their blood sugar (Type-2 diabetes is directly linked to a pancreatic dysfunction that inhibits insulin production).

However, people aren’t turning to Henry for generic GLP-1 RAs because of diabetes, at least not directly, and certainly not according to the company’s marketing. Across all of its GLP-1-related content, Henry advertises the substance as a weight loss drug — and certain GLP-1 RAs have recently been FDA-approved to treat overweight and obesity. So, this isn’t a manipulative or dishonest approach by Henry; the company is just identifying its demographic.

A GLP-1 RA’s influence over insulin production is just one prong of its weight loss action. These drugs also slow down gastric emptying, which helps you feel fuller for longer. They also act on your brain chemistry to influence feelings of satiety, reducing the potential for a hormonal imbalance signaling that you’re hungry when you aren’t.

These various mechanisms of action work together to create a situation that makes it easier to lose weight by reducing your caloric intake and improving your insulin response.

Non-GLP-1 weight loss drugs

Henry offers a pair of weight loss drugs that aren’t GLP-1 RAs. These include phentermine and topiramate. Phentermine is available on its own, but Henry only prescribes topiramate alongside phentermine. Both drugs can blunt appetite, leading to decreased caloric consumption.

These two treatments do a good job illustrating how GLP-1 RAs’ variegated mechanisms of action outperform appetite suppression alone. Compared to the double-digit weight loss percentages seen in GLP-1 RA studies, phentermine appears to generate just 1-3% weight loss after six months. Topiramate may add a modest influence on insulin to the picture, which could account for its superior performance (at least according to an animal study). Topiramate studies typically see closer to 10% body weight reduction after a year of use.

Testosterone replacement therapy (TRT)

Henry offers two drugs intended to treat low testosterone: testosterone cypionate injections and testosterone cream. Injecting testosterone cypionate has its advantages over the cream, but there are significant safety risks, as well. One issue with testosterone cypionate arises from how it causes a spike in testosterone a few days after the injection, followed by a steady decline until your next dose, with doses spaced out every 2-4 weeks. That fluctuation can cause mood swings, libido issues, and other side effects.

Transdermal testosterone treatment doesn’t cause the kinds of supratherapeutic peaks you often see with injected testosterone replacements. Unfortunately, the creams have their own set of dangers. Specifically, creams create a much higher risk of transferring the material to women or children, both of whom can experience unpleasant side effects like virilization or early-onset and accelerated puberty.

Henry offers its testosterone cream in concentrations of 1.5%, 10%, 15%, and 20%, and it’ll be up to you and your consulting medical professional to determine the best dose for your needs.

The prevalence of clinically diagnosable hypogonadism (low testosterone) in men middle-aged and older is nearly 40% in the U.S. So, it makes sense that a large population of men would be curious about testosterone replacement. Whether you opt for therapies like those offered by Henry is ultimately up to you and your doctor, but we’re aware of additional treatment paths that include oral medications like clomiphene citrate and even supplemental approaches using botanicals, amino acids, and certain vitamins and minerals to address low T before turning to TRT.

Insomnia treatment

Even elementary school textbooks take pains to impress upon students the importance of sleep. It’d be one thing if you were a night owl staying up late to spend time with family and friends, but if insomnia is robbing you of sleep — causing you to lie in bed wide awake with no number of sheep able to help you — you might want to seek medical intervention. You’re also not alone, with insufficient sleep affecting over 36% of adults in the U.S.

Henry offers three medications to treat insomnia: Hydroxyzine pamoate, trazodone, and mirtazapine. Let’s take a quick look at each medication since they can all induce sleep in different ways:

Hydroxyzine pamoate

This drug is an antihistamine typically deployed to reduce allergy-related itchiness. If you’ve ever taken Benadryl — a different drug but also an antihistamine — you know that these kinds of drugs can make you exceedingly drowsy. Clinical research also points to relatively reliable efficacy here, as well.

Trazodone

Trazodone is a somewhat controversial medication for insomnia. It’s widely prescribed, both as an antidepressant and an insomnia treatment, but a recent review suggests that it’s a poor first choice for those with insomnia. The review mostly focuses on a lack of sufficient scientific research supporting the drug’s use in treating insomnia, as well as the availability of many other options that would offer better starting points for the average patient. It also references numerous prescription guidelines from organizations like the American College of Physicians and the American Academy of Sleep Medicine advising against its use in sleep disorders.

Mirtazapine

Like trazodone, mirtazapine is an antidepressant. It also shares a somewhat controversial status as a treatment for insomnia. Numerous case studies have linked mirtazapine with an increased incidence of nightmares in users. And studies looking into the drug’s efficacy as an insomnia treatment typically also feature just one participant. Even as an antidepressant, it’s somewhat atypical, belonging to a class of drugs called noradrenergic and specific serotonergic antidepressants, which may be better at targeting specific receptors than SSRIs. Sedation appears to be a primary side effect.

Because insomnia can accompany so many psychological disorders, it’s critical to be evaluated by a medical professional. Henry’s doctors may be able to speak to certain potential causes and work with you to integrate these medications into a more comprehensive psychotherapeutic approach. You’ll have to pursue that aspect on your own, however, as Henry does not offer psychiatric or counseling services.

Who is Henry Meds for?

Henry Meds is an interesting place to seek medical treatment for anyone dealing with overweight and obesity, insomnia, or low testosterone. It’s an especially good choice for those without insurance or whose insurance doesn’t provide enough coverage to seek treatment through a traditional doctor.

Henry’s pricing makes it a far more attractive choice for those without insurance to get these drugs, as basic costs include your appointment, medication, and follow-up communications with a Henry medical professional. And if ancillary medications are necessary (like antiemetics to fight nausea from GLP-1 RAs), they’re provided at no extra cost.

Henry Meds is also a great place for anyone interested in GLP-1 RAs for weight loss but wary of needles. Some competitors, like Hims, only offer injectable versions of these drugs, but Henry provides injections or oral versions of two of the most effective and popular GLP-1 RAs on the market.

Who might want to look elsewhere?

If you have good insurance, then your copay and recurring medication costs will likely be lower through traditional medical means than through telemedicine services like Henry's. There are some exceptions to this, even with good insurance plans, but we've seen insurers work with doctors and pharmaceutical companies to provide GLP-1 RAs for very little cost. And other drugs Henry offers (non-GLP-1 medications) are all available as less expensive generics from any pharmacy, not just compounding pharmacies.

There are also various potential contraindications with certain meds provided by Henry, but we’ll get into those in our safety section below.

Is Henry Meds safe?

Henry Liraglutide with Needle

Photo by Innerbody Research

To receive any products through Henry Meds, you have to attend a telehealth appointment with a Henry medical professional, often a nurse practitioner or similar figure. This person will determine whether you’re a safe candidate for these medications, but much of their assessment will be based on answers you provide on a medical questionnaire. So, for your safety, it’s imperative that you be honest and thorough when filling it out.

Even for good candidates, Henry's medications have side effect profiles that range from mildly unpleasant to fatal. Before starting any new medicines, you'll want to understand your risks, even if it's just the risk of a little nausea.

Here, we’ll look at each medication path in Henry’s catalog and discuss various safety issues that may arise.

Weight loss drug safety

Most people looking for weight loss drugs through Henry are likely interested in generic GLP-1 RAs like those for Ozempic or Mounjaro. These drugs have pretty good safety profiles, but they all come with a few minor risks as well as the occasional serious concern.

Side effects typical of GLP-1 RAs include:

  • Nausea
  • Bloating
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Belching
  • Flatulence

Most of these symptoms are associated with these drugs' ability to slow down your digestion. As you acclimate to your body’s changing digestive rhythm and consume fewer calories per meal, these side effects tend to dissipate.

More serious complications from GLP-1 RAs include an increased risk of thyroid cancer, gallbladder disease, pancreatitis, or gastroparesis.

Phentermine and topiramate have some similar GI side effects, but both add dry mouth to the picture. Topiramate can also cause drowsiness, tremors, and some minor bleeding issues like nosebleeds or excessive menstrual bleeding.

Testosterone replacement therapy safety

Testosterone replacement therapy (TRT) poses several significant risks to those who take these drugs and those who live with the patient. Injections of testosterone cypionate — Henry’s main TRT drug — are typically administered every 2-4 weeks, during which time your testosterone levels can dramatically rise and fall. At their height, they can reach what are called supratherapeutic peaks, which is when a drug’s effect far surpasses what is necessary. These periods are often followed by a precipitated decline in testosterone until the next dose.

Long-term treatment should level this experience out slightly as your baseline testosterone level increases, but the resultant mood swings, changes in libido, and other side effects can be a constant companion in the process.

For this reason — or for the reluctance to use needles — many men prefer transdermal methods like patches, gels, or creams. Henry offers a cream, which usually requires a heftier application than a gel and doesn’t absorb or evaporate as thoroughly as a gel would. That means there’s a higher risk of unintentionally spreading the cream’s contents to anyone who comes in contact with you or surfaces you touch.

When females come into contact with this kind of exogenous testosterone, it can negatively impact their endocrine system, throwing hormones off balance and producing masculinizing effects. When children come in contact with it, it can drive virilization and early onset or accelerated puberty.

Fortunately, Henry offers testosterone cream in concentrations as low as 1.5%, which can offset some of the risk posed by its residue.

TRT has also been associated with several other common adverse effects, some of which affect the cardiovascular system and include:

  • Increased risk of atrial fibrillation, acute kidney injury, or pulmonary embolism
  • Elevation of prostate-specific antigen
  • Increased risk of prostate cancer
  • Various lower urinary tract symptoms
  • Sleep apnea
  • Erythrocytosis

If you decide to pursue TRT through Henry or most other providers, you’ll need to present certain test results to qualify for a prescription. These tests are not included in Henry’s costs.

Insomnia medication safety

Of Henry’s three insomnia medications, none are FDA-approved for insomnia treatment. Instead, they are prescribed off-label and only have FDA approval to act as antihistamines or antidepressants.

Clinical research into the efficacy and safety of trazodone or mirtazapine is currently limited enough that several prominent sleep organizations have come out against the use of either as a first step in treating sleep disorders. Hydroxyzine pamoate is the mildest of the three medications, as it’s the one antihistamine compared to the other two antidepressants. But it may not be sufficient for some insomnia cases, especially if you’ve already tried other antihistamines like Benadryl (diphenhydramine) without success.

Side effects of hydroxyzine pamoate can include:

  • Headache
  • Dry mouth
  • Confusion
  • Dizziness
  • Sedation (why it’s good for insomnia)
  • Trembling
  • Seizures

Those last two are much less common than the others, but they’re serious enough that you should watch out for them.

One of our testers developed sleep apnea symptoms while taking antihistamines for insomnia, and there is some research into the relationship between allergies and sleep apnea, as well as antihistamines’ potential effect on sleep apnea symptoms. The latter research showed a much greater risk of symptom exacerbation among patients also taking opioids. Still, you should mention to your doctor if you or anyone in your family has a history of sleep apnea — or if you’re currently using opioids — before beginning insomnia treatment with antihistamines.

Side effects of trazodone can include:

  • Changes in appetite or weight
  • Constipation
  • Diarrhea
  • Dizziness or lightheadedness
  • Dry mouth
  • Nausea
  • Nervousness
  • Nightmares
  • Muscle pain
  • Rash
  • Decreased sex drive
  • Sexual dysfunction
  • Delayed orgasm
  • Uncontrollable shaking of a part of the body
  • Stuffy nose
  • Tired, red, or itchy eyes
  • Vomiting
  • Weakness or tiredness

A rare but rather unpleasant potential side effect in men is priapism — a painful, long-lasting erection that may require surgical intervention. In fact, trazodone was investigated and occasionally used by urologists as a treatment for erectile dysfunction before the advent of PDE-5 inhibitors. As such, combining trazodone with modern ED meds may increase your risk of priapism.

Finally, side effects for mirtazapine can include:

  • Anxiousness
  • Confusion
  • Constipation
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Increased weight and appetite
  • Nausea
  • Vomiting

Mirtazapine has a reasonably mild side effect profile, but those side effects are fairly common. More than 25% of participants in one study experienced dry mouth, with over 9% reporting increased insomnia and nearly 25% experiencing changes in appetite.

With so many potential side effects and contraindications for all of the medications available through Henry Meds, it’s imperative that the company provides you with thorough and considered consultations. In our testing experience, we found Henry’s medical professionals to be exceptionally thorough, asking detailed questions about the answers provided on our intake questionnaires and even discussing the reasoning behind their lines of inquiry.

Henry Meds consultation process

When we set out to test Henry, we went through the entire process, from browsing the site for products to meeting with a doctor and receiving medication and support. We’ve had similar experiences with dozens of telehealth providers, and we compared our experience with Henry to those to see how Henry stacks up against them.

Here’s what the process looks like:

  1. Find a product on the Henry Meds site that interests you
  2. Sign up and pay for the first installment of the associated subscription
  3. Fill out a thorough questionnaire
  4. Upload images of a government-issued ID
  5. Set an appointment with a Henry medical professional
  6. Take any required medical tests at a local lab or upload recent results
  7. Attend the appointment
  8. Receive medication and begin treatment as directed

Our experiences with Henry-associated medical professionals — all nurse practitioners in our testing — were universally positive. We found them patient, friendly, and informative. The only downside was that appointments were generally one week away from our signup dates. One of the advantages of telehealth is supposed to be speed, especially compared to incredibly long wait times to see certain doctors. One week is still much faster than the in-person norm, but we’re used to meeting with telehealth doctors within a couple of days.

Henry Meds pricing

Henry’s pricing is one of its strongest attributes, as prices for similar treatments from competitors are often slightly or significantly higher. The fact that Henry doesn't charge a membership fee on top of its medication programs is an additional benefit.

Let’s break down the cost of Henry’s current lineup:

First month promotional costRecurring monthly cost
GLP-1 RA injections$247$297
Oral tirzepatide$299$349
Oral semaglutide$199$249
Testosterone$79$129
Insomnia medication$29$59
Phentermine or topiramate and phentermineN/A$149

These prices are among the lowest you’ll find for generic GLP-1 RAs, though advertised prices from some competitors may confuse the issue a bit. For example, Hims advertises an injectable semaglutide for $199/month with no membership fees. But that’s the cost of your first month, which requires a lower semaglutide dose. As you titrate up to the maintenance dose, the price increases correspondingly. At that maintenance dose, you’ll pay $399/month from Hims, whereas Henry charges just $297/month — more than $100 less.

If you need a stronger dose than the typical maintenance dose, Henry may increase your price. Increased doses come with an upcharge of $100/month.

Shipping on any and all Henry medications is free, and if your doctor prescribes you a complementary treatment, like anti-nausea meds for GLP-1 RA patients, they’re included for free.

Note that billing cycles start the day you sign up, so if you have to wait a week for an appointment and another few days for your prescription to arrive, you may find yourself getting billed for the next month’s shipment less than three weeks later.

Henry’s money-back guarantee and cancellation policy

Henry offers a 30-day money-back guarantee on all of its prescriptions, which is far more generous than most competitors. However, it’s important to note that, like the billing cycle, the 30-day countdown starts the day you sign up. You might only get a couple of weeks to try your medication out before determining to continue treatment.

For some medications, like insomnia pills, this is enough time to evaluate efficacy. But GLP-1 RAs and testosterone replacement can take several weeks to several months to create noticeable results. Even a full 30 days wouldn’t be enough to judge their efficacy.

Alternatives to Henry Meds

The explosion in popularity of weight loss drugs like Ozempic has caused numerous telehealth companies to offer access to brand-name and generic versions of these drugs. That makes Henry one of many avenues you can take to access them. In our research, we’ve found that Henry’s prices are among the best, but there may be viable alternatives for certain medications, especially as your insurance picture differs from another person’s.

Let’s take a look at some of these alternatives to Henry Meds based on the profiles of people who might benefit from them:

Your insurance covers brand-name GLP-1 RAs

Depending on your insurance plan, you may be able to pay very little for access to brand-name weight loss drugs like Ozempic. In that case, you could go through some of Henry’s telehealth competitors like Hims or Found. But some of these companies charge membership fees on top of the cost of medication, and those fees are likely higher than the copay for a doctor’s appointment to get a prescription. Hims lacks a membership fee, but its base prices for brand-name GLP-1 RAs are higher than average retail. In these cases, starting with an in-person appointment would likely be wiser than going through Henry or one of its competitors.

You want an alternative testosterone therapy

Testosterone cypionate and testosterone cream from Henry aren’t the best options for everyone. There are other drugs that can boost testosterone with less intense swings in T levels, less risk to children and women, and no need for needles. Again, while some of Henry’s competitors offer these alternatives, your insurance may cover treatment if your test reveals low testosterone. If you’re insured, making an appointment with a urologist or endocrinologist would likely save you money.

You want a different approach to sleep support

Henry’s options for insomnia support leave a bit to be desired. Some competitors offer drugs with FDA approval specifically for insomnia, like ramelteon from RedBoxRx. There are also many non-pharmaceutical approaches to insomnia, including talk therapy.

As you can see, the conditions that would send you away from Henry are pretty specific, but alternatives certainly exist if you find these apply to you.

FAQ about Henry Meds

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Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

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